LMPD Database

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LMP006911

UniProt Annotations

Entry Information
Gene NameHfd1p
Protein EntryHFD1_YEAST
UniProt IDQ04458
SpeciesYeast (S288c)
Comments
Comment typeDescription
Catalytic ActivityAn aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
FunctionCatalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid. {ECO:0000269|PubMed:22633490}.
MiscellaneousPresent with 2930 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the aldehyde dehydrogenase family. {ECO:0000305}.
Subcellular LocationMitochondrion outer membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Endosome membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Cytoplasmic granule membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.