LMPD Database

LMP006717

Record overview

LMPD IDLMP006717
Gene ID79135
SpeciesHomo sapiens (Human)
Gene Nameapolipoprotein O
Gene SymbolAPOO
SynonymsFAM121B
Alternate namesapolipoprotein O; brain my025; family with sequence similarity 121B
ChromosomeX
Map LocationXp22.11
SummaryThis gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16.[provided by RefSeq, Sep 2009]
OrthologsView orthologs and multiple alignments for APOO

Proteins

apolipoprotein O precursor
Refseq ID:NP_077027
Protein GI:13129148
UniProt ID:Q9BUR5
mRNA ID:NM_024122
Length:198
RefSeq Status:REVIEWED
MFKVIQRSVGPASLSLLTFKVYAAPKKDSPPKNSVKVDELSLYSVPEGQSKYVEEARSQLEESISQLRHYCEPYTTWCQETYSQTKPKMQSLVQWGLDSY
DYLQNAPPGFFPRLGVIGFAGLIGLLLARGSKIKKLVYPPGFMGLAASLYYPQQAIVFAQVSGERLYDWGLRGYIVIEDLWKENFQKPGNVKNSPGTK
 
sig_peptide: 1..23
calculated_mol_wt: 2556
peptide sequence: 
MFKVIQRSVGPASLSLLTFKVYA

mat_peptide: 24..198
product: apolipoprotein O
calculated_mol_wt: 19747
peptide sequence: 
APKKDSPPKNSVKVDELSLYSVPEGQSKYVEEARSQLEESISQLRHYCEPYTTWCQETYSQTKPKMQSLVQWGLDSYDYLQNAPPGFFPRLGVIGFAGLI
GLLLARGSKIKKLVYPPGFMGLAASLYYPQQAIVFAQVSGERLYDWGLRGYIVIEDLWKENFQKPGNVKNSPGTK