LMPD Database

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LMP006695

UniProt Annotations

Entry Information
Gene Namesyntaxin 12
Protein EntrySTX12_HUMAN
UniProt IDQ86Y82
SpeciesHuman
Comments
Comment typeDescription
FunctionSNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network. The SNARE complex containing STX6, STX12, VAMP4 and VTI1A mediates vesicle fusion (in vitro) (By similarity).
InteractionO95477:ABCA1; NbExp=9; IntAct=EBI-2691717, EBI-784112;
Sequence CautionSequence=CAA22911.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ;
SimilarityBelongs to the syntaxin family.
SimilarityContains 1 t-SNARE coiled-coil homology domain.
Subcellular LocationEndosome membrane ; Single-pass type IV membrane protein . Golgi apparatus membrane {ECO
SubunitInteracts with NAPA and SNAP23. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A (By similarity). Associates with the BLOC-1 complex. Interacts with BLOC1S6.