LMPD Database

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LMP004322

UniProt Annotations

Entry Information
Gene Nameasparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)
Protein EntryALG1_MOUSE
UniProt IDQ921Q3
SpeciesMouse
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q921Q3-1; Sequence=Displayed; Name=2; IsoId=Q921Q3-2; Sequence=VSP_032516;
Catalytic ActivityGDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-1,4-D-mannosylchitobiosyldiphosphodolichol.
FunctionParticipates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (By similarity). {ECO:0000250}.
PathwayProtein modification; protein glycosylation.
Sequence CautionSequence=BC011281; Type=Frameshift; Positions=462; Evidence={ECO:0000305};
SimilarityBelongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.