LMPD Database

LMP003143

Gene Information

Entrez Gene ID	2053
Gene Name	epoxide hydrolase 2, cytoplasmic
Gene Symbol	EPHX2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	IDA:UniProtKB	C	cytosol
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005777	IDA:UniProtKB	C	peroxisome
GO:0033885	IEA:UniProtKB-EC	F	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity
GO:0004301	IDA:UniProtKB	F	epoxide hydrolase activity
GO:0042577	IDA:UniProtKB	F	lipid phosphatase activity
GO:0000287	IDA:UniProtKB	F	magnesium ion binding
GO:0016791	IDA:UniProtKB	F	phosphatase activity
GO:0042803	IDA:UniProtKB	F	protein homodimerization activity
GO:0005102	IPI:UniProtKB	F	receptor binding
GO:0015643	IDA:UniProtKB	F	toxic substance binding
GO:0019369	TAS:Reactome	P	arachidonic acid metabolic process
GO:0006874	NAS:UniProtKB	P	cellular calcium ion homeostasis
GO:0042632	IDA:UniProtKB	P	cholesterol homeostasis
GO:0016311	IDA:UniProtKB	P	dephosphorylation
GO:0017144	NAS:UniProtKB	P	drug metabolic process
GO:0019373	TAS:Reactome	P	epoxygenase P450 pathway
GO:0006954	NAS:UniProtKB	P	inflammatory response
GO:0046839	IDA:UniProtKB	P	phospholipid dephosphorylation
GO:0010628	IDA:UniProtKB	P	positive regulation of gene expression
GO:0045909	NAS:UniProtKB	P	positive regulation of vasodilation
GO:0072593	NAS:UniProtKB	P	reactive oxygen species metabolic process
GO:0008217	NAS:UniProtKB	P	regulation of blood pressure
GO:0090181	IMP:UniProtKB	P	regulation of cholesterol metabolic process
GO:0009636	NAS:UniProtKB	P	response to toxic substance
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0046272	IDA:UniProtKB	P	stilbene catabolic process
GO:0006805	NAS:UniProtKB	P	xenobiotic metabolic process

KEGG Pathway Links

KEGG Pathway ID	Description
hsa00590	Arachidonic acid metabolism
hsa04146	Peroxisome

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_150417	Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)