LMPD Database

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LMP002568

Gene Information

Entrez Gene ID5742
Gene Nameprostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Gene SymbolPTGS1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0043231 ISS:UniProtKBCintracellular membrane-bounded organelle
GO:0005634 ISS:UniProtKBCnucleus
GO:0001750 IEA:EnsemblCphotoreceptor outer segment
GO:0051213 IEA:UniProtKB-KWFdioxygenase activity
GO:0020037 IEA:InterProFheme binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004601 TAS:ReactomeFperoxidase activity
GO:0004666 IDA:BHF-UCLFprostaglandin-endoperoxide synthase activity
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0019371 IDA:BHF-UCLPcyclooxygenase pathway
GO:0006954 IEA:InterProPinflammatory response
GO:0006629 NAS:ProtIncPlipid metabolic process
GO:0001516 ISS:UniProtKBPprostaglandin biosynthetic process
GO:0008217 ISS:UniProtKBPregulation of blood pressure
GO:0042127 IEA:EnsemblPregulation of cell proliferation
GO:0006979 IEA:InterProPresponse to oxidative stress
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006805 TAS:ReactomePxenobiotic metabolic process
KEGG Pathway Links
KEGG Pathway IDDescription
hsa04611Platelet activation
hsa04726Serotonergic synapse
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150149Synthesis of Prostaglandins (PG) and Thromboxanes (TX)