LMPD Database

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LMP001872

UniProt Annotations

Entry Information
Gene NameELOVL fatty acid elongase 3
Protein EntryELOV3_HUMAN
UniProt IDQ9HB03
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityA very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
DomainThe di-lysine motif may confer endoplasmic reticulum localization.
FunctionCondensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Highest activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs.
PtmN-Glycosylated.
SimilarityBelongs to the ELO family.
Subcellular LocationEndoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue SpecificityTestis.