LMPD Database

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LMP001639

UniProt Annotations

Entry Information
Gene Namephosphate cytidylyltransferase 1, choline, beta
Protein EntryPCY1B_HUMAN
UniProt IDQ9Y5K3
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=4; Name=2; IsoId=Q9Y5K3-1; Sequence=Displayed; Name=1; IsoId=Q9Y5K3-2; Sequence=VSP_001226; Name=3; IsoId=Q9Y5K3-3; Sequence=VSP_020045, VSP_020046; Note=No experimental confirmation available.; Name=4; IsoId=Q9Y5K3-4; Sequence=VSP_044659; Note=No experimental confirmation available.;
Catalytic ActivityCTP + phosphocholine = diphosphate + CDP- choline.
FunctionControls phosphatidylcholine synthesis.
PathwayPhospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2.
PtmExtensively phosphorylated. The beta-1 isoform seems to be much less phosphorylated.
SimilarityBelongs to the cytidylyltransferase family.
Subcellular LocationEndoplasmic reticulum.
Tissue SpecificityHighly expressed in testis, placenta, brain, ovary and fetus.
Web ResourceName=SeattleSNPs; URL="http://pga.gs.washington.edu/data/pcyt1b/";