LMPD Database

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LMP000484

UniProt Annotations

Entry Information
Gene Namephospholipase A2, group XV
Protein EntryPAG15_HUMAN
UniProt IDQ8NCC3
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q8NCC3-1; Sequence=Displayed; Name=2; IsoId=Q8NCC3-2; Sequence=VSP_056689, VSP_056690; Note=No experimental confirmation available.;
FunctionHas transacylase and calcium-independent phospholipase A2 activity. Catalyzes the formation of 1-O-acyl-N- acetylsphingosine and the concomitant release of a lyso- phospholipid (By similarity). May have weak lysophospholipase activity.
PtmN-glycosylated.
Sequence CautionSequence=CAB53675.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the AB hydrolase superfamily. Lipase family.
Subcellular LocationLysosome . Secreted .
Tissue SpecificityHighly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.