LMPD Database

LMP000440

Gene Information

Entrez Gene ID	11450
Gene Name	adiponectin, C1Q and collagen domain containing
Gene Symbol	Adipoq
Species	Mus musculus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0071944	ISS:UniProtKB	C	cell periphery
GO:0009986	ISS:BHF-UCL	C	cell surface
GO:0005581	IEA:UniProtKB-KW	C	collagen trimer
GO:0005783	IDA:MGI	C	endoplasmic reticulum
GO:0005615	IDA:MGI	C	extracellular space
GO:0070062	IEA:Ensembl	C	extracellular vesicular exosome
GO:0048471	ISS:UniProtKB	C	perinuclear region of cytoplasm
GO:0005179	IDA:MGI	F	hormone activity
GO:0042802	IPI:IntAct	F	identical protein binding
GO:0005102	IDA:MGI	F	receptor binding
GO:0033691	IEA:Ensembl	F	sialic acid binding
GO:0033211	IEA:Ensembl	P	adiponectin-activated signaling pathway
GO:0050873	IDA:MGI	P	brown fat cell differentiation
GO:0071320	IEA:Ensembl	P	cellular response to cAMP
GO:0035690	IDA:UniProtKB	P	cellular response to drug
GO:0071872	IEA:Ensembl	P	cellular response to epinephrine stimulus
GO:0032869	IGI:MGI	P	cellular response to insulin stimulus
GO:0007623	IEA:Ensembl	P	circadian rhythm
GO:0070994	IMP:UniProtKB	P	detection of oxidative stress
GO:0006635	IMP:MGI	P	fatty acid beta-oxidation
GO:0019395	IDA:MGI	P	fatty acid oxidation
GO:0042593	IDA:MGI	P	glucose homeostasis
GO:0006006	IDA:MGI	P	glucose metabolic process
GO:0034383	ISS:UniProtKB	P	low-density lipoprotein particle clearance
GO:0051899	IEA:Ensembl	P	membrane depolarization
GO:0060081	IEA:Ensembl	P	membrane hyperpolarization
GO:0045776	ISS:UniProtKB	P	negative regulation of blood pressure
GO:0030336	IDA:UniProtKB	P	negative regulation of cell migration
GO:2000279	ISS:UniProtKB	P	negative regulation of DNA biosynthetic process
GO:0070373	ISS:UniProtKB	P	negative regulation of ERK1 and ERK2 cascade
GO:0045599	IDA:BHF-UCL	P	negative regulation of fat cell differentiation
GO:0045721	IDA:MGI	P	negative regulation of gluconeogenesis
GO:0030853	ISS:UniProtKB	P	negative regulation of granulocyte differentiation
GO:0034115	ISS:UniProtKB	P	negative regulation of heterotypic cell-cell adhesion
GO:0046888	IEA:Ensembl	P	negative regulation of hormone secretion
GO:0043124	ISS:UniProtKB	P	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050728	IDA:UniProtKB	P	negative regulation of inflammatory response
GO:0090317	ISS:UniProtKB	P	negative regulation of intracellular protein transport
GO:0045715	ISS:UniProtKB	P	negative regulation of low-density lipoprotein particle receptor biosynthetic process
GO:0010745	ISS:UniProtKB	P	negative regulation of macrophage derived foam cell differentiation
GO:0045650	ISS:UniProtKB	P	negative regulation of macrophage differentiation
GO:0043407	IDA:UniProtKB	P	negative regulation of MAP kinase activity
GO:2000590	IDA:UniProtKB	P	negative regulation of metanephric mesenchymal cell migration
GO:0050765	ISS:UniProtKB	P	negative regulation of phagocytosis
GO:2000584	IDA:UniProtKB	P	negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
GO:0010642	IDA:UniProtKB	P	negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0031953	ISS:UniProtKB	P	negative regulation of protein autophosphorylation
GO:1900121	ISS:UniProtKB	P	negative regulation of receptor binding
GO:0014912	ISS:UniProtKB	P	negative regulation of smooth muscle cell migration
GO:0048662	ISS:UniProtKB	P	negative regulation of smooth muscle cell proliferation
GO:0050805	ISS:UniProtKB	P	negative regulation of synaptic transmission
GO:0045892	IMP:UniProtKB	P	negative regulation of transcription, DNA-templated
GO:0010804	ISS:UniProtKB	P	negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0032720	ISS:UniProtKB	P	negative regulation of tumor necrosis factor production
GO:0045777	IEA:Ensembl	P	positive regulation of blood pressure
GO:2000481	IMP:UniProtKB	P	positive regulation of cAMP-dependent protein kinase activity
GO:0032270	ISS:BHF-UCL	P	positive regulation of cellular protein metabolic process
GO:0010875	ISS:BHF-UCL	P	positive regulation of cholesterol efflux
GO:0045923	IMP:MGI	P	positive regulation of fatty acid metabolic process
GO:0046326	IDA:MGI	P	positive regulation of glucose import
GO:2000467	ISS:UniProtKB	P	positive regulation of glycogen (starch) synthase activity
GO:0043123	IDA:MGI	P	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032757	ISS:UniProtKB	P	positive regulation of interleukin-8 production
GO:2000478	IMP:UniProtKB	P	positive regulation of metanephric glomerular visceral epithelial cell development
GO:0071639	ISS:UniProtKB	P	positive regulation of monocyte chemotactic protein-1 production
GO:0033034	ISS:UniProtKB	P	positive regulation of myeloid cell apoptotic process
GO:0050731	IEA:Ensembl	P	positive regulation of peptidyl-tyrosine phosphorylation
GO:0010739	ISS:UniProtKB	P	positive regulation of protein kinase A signaling
GO:0001934	ISS:UniProtKB	P	positive regulation of protein phosphorylation
GO:2000534	IMP:UniProtKB	P	positive regulation of renal albumin absorption
GO:0009967	IDA:MGI	P	positive regulation of signal transduction
GO:0070208	IPI:MGI	P	protein heterotrimerization
GO:0051260	IDA:MGI	P	protein homooligomerization
GO:0072659	ISS:UniProtKB	P	protein localization to plasma membrane
GO:0010906	ISS:UniProtKB	P	regulation of glucose metabolic process
GO:0014823	IEA:Ensembl	P	response to activity
GO:0045471	IEA:Ensembl	P	response to ethanol
GO:0051384	IEA:Ensembl	P	response to glucocorticoid
GO:0009749	IDA:MGI	P	response to glucose
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0070543	IEA:Ensembl	P	response to linoleic acid
GO:0007584	IEA:Ensembl	P	response to nutrient
GO:0009744	IEA:Ensembl	P	response to sucrose
GO:0034612	ISS:UniProtKB	P	response to tumor necrosis factor

KEGG Pathway Links

KEGG Pathway ID	Description
mmu04152	AMPK signaling pathway
mmu04932	Non-alcoholic fatty liver disease (NAFLD)