LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP013310

UniProt Annotations

Entry Information
Gene Namediacylglycerol lipase, alpha
Protein EntryDGLA_RAT
UniProt IDQ5YLM1
SpeciesRat
Comments
Comment typeDescription
CofactorName=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence= ;
FunctionCatalyzes the hydrolysis of diacylglycerol (DAG) to 2- arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses (By similarity)
SimilarityBelongs to the AB hydrolase superfamily. Lipase family
Subcellular LocationCell membrane ; Multi-pass membrane protein .