LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012892

UniProt Annotations

Entry Information
Gene Namesialidase 3 (membrane sialidase)
Protein EntryNEUR3_RAT
UniProt IDQ99PW5
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityHydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
FunctionPlays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates
SimilarityBelongs to the glycosyl hydrolase 33 family
SimilarityContains 3 BNR repeats
Subcellular LocationCell membrane ; Peripheral membrane protein .
Tissue SpecificityExpressed in brain, cardiac muscle and weakly in liver.