LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012846

UniProt Annotations

Entry Information
Gene Nameperoxisomal trans-2-enoyl-CoA reductase
Protein EntryPECR_RAT
UniProt IDQ9WVK3
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.
FunctionParticipates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity (By similarity)
InductionUp-regulated by fasting
PathwayLipid metabolism; fatty acid biosynthesis.
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family
Subcellular LocationPeroxisome .
SubunitInteracts with PEX5, probably required to target it into peroxisomes
Tissue SpecificityHighly expressed in liver and kidney. Weakly expressed in other tissues