LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012701

UniProt Annotations

Entry Information
Gene Namesynaptotagmin IV
Protein EntrySYT4_RAT
UniProt IDP50232
SpeciesRat
Comments
Comment typeDescription
CofactorName=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence= ; Note=Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains. ;
FunctionMay be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.
InteractionP49187:Mapk10; NbExp=2; IntAct=EBI-540118, EBI-7155513; P49185:Mapk8; NbExp=5; IntAct=EBI-540118, EBI-7456505;
SimilarityBelongs to the synaptotagmin family
SimilarityContains 2 C2 domains. {ECO:0000255|PROSITE- ProRule:PRU00041}.
Subcellular LocationCytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.