LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP012511

UniProt Annotations

Entry Information
Gene Namecytochrome P450, family 7, subfamily b, polypeptide 1
Protein EntryCP7B1_RAT
UniProt IDQ63688
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityCholest-5-ene-3-beta,25-diol + NADPH + O(2) = cholest-5-ene-3-beta,7-alpha,25-triol + NADP(+) + H(2)O.
Catalytic ActivityCholest-5-ene-3-beta,27-diol + NADPH + O(2) = cholest-5-ene-3-beta,7-alpha,27-triol + NADP(+) + H(2)O.
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Evidence= ;
PathwayLipid metabolism; bile acid biosynthesis.
SimilarityBelongs to the cytochrome P450 family
Subcellular LocationEndoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue SpecificityHighly expressed in brain; also expressed in liver and kidney.