LIPID MAPS® Gene/Proteome Database (LMPD)

Introduction | Overview of Interfaces | Browse | Search | Download

LMPD Record

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP012486

Gene Information

Entrez Gene ID25262
Gene Nameinositol 1,4,5-trisphosphate receptor, type 1
Gene SymbolItpr1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005955 IEA:EnsemblCcalcineurin complex
GO:0005789 IEA:EnsemblCendoplasmic reticulum membrane
GO:0005637 IEA:EnsemblCnuclear inner membrane
GO:0005730 IEA:EnsemblCnucleolus
GO:0031088 IEA:EnsemblCplatelet dense granule membrane
GO:0031094 IEA:EnsemblCplatelet dense tubular network
GO:0014069 IEA:EnsemblCpostsynaptic density
GO:0016529 IEA:EnsemblCsarcoplasmic reticulum
GO:0005218 IEA:EnsemblFintracellular ligand-gated calcium channel activity
GO:0035091 IEA:EnsemblFphosphatidylinositol binding
GO:0032469 IEA:EnsemblPendoplasmic reticulum calcium ion homeostasis
GO:0070059 IEA:EnsemblPintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0009791 IEA:EnsemblPpost-embryonic development
GO:0051209 IEA:EnsemblPrelease of sequestered calcium ion into cytosol
GO:0001666 IEA:EnsemblPresponse to hypoxia
GO:0050882 IEA:EnsemblPvoluntary musculoskeletal movement
KEGG Pathway Links
KEGG Pathway IDDescription
ko05010Alzheimer's disease
rno05010Alzheimer's disease
ko04020Calcium signaling pathway
rno04020Calcium signaling pathway
ko04022cGMP-PKG signaling pathway
rno04022cGMP-PKG signaling pathway
rno04725Cholinergic synapse
ko04713Circadian entrainment
rno04713Circadian entrainment
ko04728Dopaminergic synapse
rno04728Dopaminergic synapse
ko04915Estrogen signaling pathway
rno04915Estrogen signaling pathway
ko04540Gap junction
rno04540Gap junction
ko04971Gastric acid secretion
rno04971Gastric acid secretion
ko04724Glutamatergic synapse
rno04724Glutamatergic synapse
ko04912GnRH signaling pathway
rno04912GnRH signaling pathway
ko05016Huntington's disease
rno05016Huntington's disease
ko04750Inflammatory mediator regulation of TRP channels
rno04750Inflammatory mediator regulation of TRP channels
ko04730Long-term depression
rno04730Long-term depression
ko04720Long-term potentiation
rno04720Long-term potentiation
ko04114Oocyte meiosis
rno04114Oocyte meiosis
ko04921Oxytocin signaling pathway
rno04921Oxytocin signaling pathway
ko04972Pancreatic secretion
rno04972Pancreatic secretion
ko04070Phosphatidylinositol signaling system
rno04070Phosphatidylinositol signaling system
rno04611Platelet activation
ko05205Proteoglycans in cancer
rno05205Proteoglycans in cancer
ko04723Retrograde endocannabinoid signaling
rno04723Retrograde endocannabinoid signaling
ko04970Salivary secretion
rno04970Salivary secretion
rno04726Serotonergic synapse
ko04918Thyroid hormone synthesis
rno04918Thyroid hormone synthesis
ko04270Vascular smooth muscle contraction
rno04270Vascular smooth muscle contraction
REACTOME Pathway Links
REACTOME Pathway IDDescription
5953415Adaptive Immune System
5953413Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
5953802beta-catenin independent WNT signaling
5953801Ca2+ pathway
5954237cGMP effects
5953392DAG and IP3 signaling
5953408DAP12 interactions
5953407DAP12 signaling
5953253Disease
5953399Downstream signaling of activated FGFR
5953396Downstream signal transduction
5953655Effects of PIP2 hydrolysis
5953402EGFR interacts with phospholipase C-gamma
5953656Elevation of cytosolic Ca2+ levels
5953417Fc epsilon receptor (FCERI) signaling
5953416FCERI mediated Ca+2 mobilization
5953784Fcgamma receptor (FCGR) dependent phagocytosis
5953653G alpha (q) signalling events
5953537Gastrin-CREB signalling pathway via PKC and MAPK
5954168Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
5953642GPCR downstream signaling
5953389G-protein mediated events
5953645Hemostasis
5953410Immune System
5953409Innate Immune System
5953611Integration of energy metabolism
5953250Metabolism
5953394NGF signalling via TRKA from the plasma membrane
5954207Nitric oxide stimulates guanylate cyclase
5953390Opioid Signalling
5953398Phospholipase C-mediated cascade
5953644Platelet activation, signaling and aggregation
5953657Platelet calcium homeostasis
5953658Platelet homeostasis
5953388PLC beta mediated events
5953405PLCG1 events in ERBB2 signaling
5953393PLC-gamma1 signalling
5953749Regulation of insulin secretion
5953783Role of phospholipids in phagocytosis
5953403Signaling by EGFR
5953404Signaling by EGFR in Cancer
5953406Signaling by ERBB2
5953400Signaling by FGFR
5953401Signaling by FGFR in disease
5953391Signaling by GPCR
5953397Signaling by PDGF
5953414Signaling by the B Cell Receptor (BCR)
5953420Signaling by VEGF
5953803Signaling by Wnt
5953395Signalling by NGF
5953381Signal Transduction
5953419VEGFA-VEGFR2 Pathway
5953418VEGFR2 mediated cell proliferation