LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP011931

UniProt Annotations

Entry Information
Gene Name3-hydroxy-3-methylglutaryl-CoA reductase b
Protein EntryQ58ER2_DANRE
UniProt IDQ58ER2
SpeciesZebrafish
Comments
Comment typeDescription
Catalytic Activity(R)-mevalonate + CoA + 2 NADP(+) = (S)-3- hydroxy-3-methylglutaryl-CoA + 2 NADPH.
PathwayMetabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.
SimilarityBelongs to the HMG-CoA reductase family.
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein.