LIPID MAPSĀ® Gene/Proteome Database (LMPD)

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LMPD Record

LMP011600

UniProt Annotations

Entry Information
Gene NameUDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
Protein EntryB3G5A_DANRE
UniProt IDQ7T3S5
SpeciesZebrafish
Comments
Comment typeDescription
Catalytic ActivityUDP-N-acetyl-D-glucosamine + beta-D- galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N- acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D- glucosyl-(1<->1)-ceramide.
Developmental StageExpressed in 2 distinct phases during the embryogenesis. The early phase extends from late blastulation to the completion of epiboly, during which the expression occurs in the superficial layer of the embryos. The second phase of expression starts during mid-segmentation and persists until day 3, during which the expression occurs prominently in the developing lens. {ECO:0000269|PubMed:14579371}.
FunctionBeta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids. {ECO:0000250}.
InductionHedgehog signaling is required for expression in embryonic lens. {ECO:0000269|PubMed:14579371}.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 31 family. {ECO:0000305}.
Subcellular LocationGolgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.