LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP011305

UniProt Annotations

Entry Information
Gene NameSphingosine-1-phosphate lyase
Protein EntrySGPL_ARATH
UniProt IDQ9C509
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivitySphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde. {ECO:0000269|PubMed:17635905, ECO:0000269|PubMed:18849574}.
CofactorName=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000250};
Disruption PhenotypeNo visible phenotype under normal growth conditions. {ECO:0000269|PubMed:18849574}.
FunctionCleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. May play a minor role in maintenance of sphingolipid metabolism during normal plant development and growth, but be required for maintaining sphingoid long chain bases (LCB) and their phosphorylated derivatives (LCB-P) levels when sphingolipid metabolism is perturbed. May play a role in dehydration stress. {ECO:0000269|PubMed:17635905, ECO:0000269|PubMed:18849574}.
PathwayLipid metabolism; sphingolipid metabolism.
Sequence CautionSequence=AAM62669.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
SimilarityBelongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305|PubMed:17635905, ECO:0000305|PubMed:18849574}; Single-pass type III membrane protein {ECO:0000305|PubMed:17635905, ECO:0000305|PubMed:18849574}.
Tissue SpecificityExpressed in the peripheral parts of leaves and the bases of trichomes. {ECO:0000269|PubMed:18849574}.