LIPID MAPS® Gene/Proteome Database (LMPD)

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LMP011156

UniProt Annotations

Entry Information
Gene Nametrigalactosyldiacylglycerol 1
Protein EntryTGD1_ARATH
UniProt IDQ8L4R0
SpeciesArabidopsis
Comments
Comment typeDescription
CautionWas originally (PubMed:18299247) thought to belong to the ABC transporter family. Lacks the conserved ABC domain, which is one of the features of the ABC transporter family. {ECO:0000305|PubMed:18299247}.
Disruption PhenotypeDisruption in the biosynthesis of ER-derived thylakoid lipids, and accumulation of oligogalactolipids, triacylglycerols (TAGs), and phosphatidates (PAs). Reduced growth with stout leaves and siliques. Impaired embryogenesis. {ECO:0000269|PubMed:12743031, ECO:0000269|PubMed:16199613}.
FunctionRequired during embryogenesis. Permease involved in lipid transfer from the endoplasmic reticulum (ER) to plastids, and necessary for thylakoids formation. {ECO:0000269|PubMed:12743031, ECO:0000269|PubMed:16199613, ECO:0000269|PubMed:18689504}.
Sequence CautionSequence=AAG12551.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the MlaE permease family. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast inner membrane {ECO:0000269|PubMed:12743031, ECO:0000269|PubMed:16199613, ECO:0000269|PubMed:18431481}; Multi-pass membrane protein {ECO:0000269|PubMed:12743031, ECO:0000269|PubMed:16199613, ECO:0000269|PubMed:18431481}.
SubunitPermease subunit of a probable lipid translocator at the inner chloroplast envelope membrane made of TGD1, TGD2 and TGD3. {ECO:0000305}.
Tissue SpecificityHigh levels in green tissues, but low levels in nongreen tissues such as roots. {ECO:0000269|PubMed:12743031}.