LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP010813

Record overview

LMPD IDLMP010813
Gene ID829610
SpeciesArabidopsis thaliana (Arabidopsis)
Gene Namephosphatidylinositol transfer protein COW1
Gene SymbolCOW1
SynonymsCAN OF WORMS1; COW1; SHORT ROOT HAIR 1; SRH1; T4L20.160; T4L20_160
Alternate namesphosphatidylinositol transfer protein COW1
Chromosome4
SummaryEncodes COW1 (can of worms1), a phosphatidylinositol transfer protein essential for root hair tip growth. The N-terminus of the COW1 protein is 32% identical to an essential phosphatidylinositol transfer protein (PITP), the yeast Sec14 protein (sec14p) while the C-terminus is 34.5% identical to a late nodulin of Lotus japonicus, Nlj16. Expression of COW1 complements the growth defect associated with Sec14p dysfunction in yeast. GFP fused to the COW1 protein specifically accumulates at the site of root hair outgrowth.
OrthologsView orthologs and multiple alignments for COW1

Proteins

phosphatidylinositol transfer protein COW1
Refseq ID:NP_195184
Protein GI:79497100
UniProt ID:F4JLE5
mRNA ID:NM_119624
Length:554
RefSeq Status:REVIEWED
MAETKPEIEMSEEERKIVKISSLKKKAINASNRFKNSFKKKGRRSSSRVMSVPIEDDIDAEDLQALDAFRQALILDELLPSKLDDLHMMLRFLRARKFDI
EKAKQMWSDMIQWRKDFGADTIIEDFDFEEIDEVMKHYPQGYHGVDKEGRPVYIERLGQIDANKLLQVTTMDRYVKYHVKEFEKTFKVKFPSCSVAANKH
IDQSTTILDVQGVGLKNFSKSARELLQRLCKIDNENYPETLNRMFIINAGSGFRLLWSTVKSFLDPKTTAKIHVLGNKYHSKLLEVIDASELPEFFGGAC
TCEDKGGCMRSDKGPWNDPEVLKIAINREAKCSPISEDEHKHVDQGRSTSGFESLERIKKKTDEDNVYEKQIATIDKSMDMAWLAKTQKAENFPISKGLE
CYVRKGAPKKGDGLLVGGVMAFVMGIVAMVRLSKDVPRKLTEAALYGNSVCYEESTKSKQNQGQFAAPVSSSEYMLMVKRMAELEDKCMFLDLKPAHVES
EKEEKLQAALNRVQVLEQELTETKKALEEALVSQKEILAYIEKKKKKKKLFFGF