LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP010684

Record overview

LMPD IDLMP010684
Gene ID838800
SpeciesArabidopsis thaliana (Arabidopsis)
Gene Namenuclear transcription factor Y subunit B-9
Gene SymbolLEC1
SynonymsEMB 212; EMB212; EMBRYO DEFECTIVE 212; LEAFY COTYLEDON 1; LEC1; NF-YB9; NUCLEAR FACTOR Y; SUBUNIT B9; T26F17.20; T26F17_20
Alternate namesnuclear transcription factor Y subunit B-9
Chromosome1
SummaryTranscriptional activator of genes required for both embryo maturation and cellular differentiation. Sequence is similar to HAP3 subunit of the CCAAT-box binding factor. HAP3 subunit is divided into three domains: an amino-terminal A domain, a central B domain, and a carboxyl-terminal C domain. LEC1 shared high similarity with other HAP3 homologs only in central, B domain. LEC1 is required for the specification of cotyledon identity and the completion of embryo maturation. It was sufficient to induce embryogenic programs in vegetative cells, suggesting that LEC1 is a major embryonic regulator that mediates the switch between embryo and vegetative development. Mutants are desiccation intolerant, have trichomes on cotyledons and exhibit precocious meristem activation. Levels of the ABI3 and FUS3 transcripts were significantly reduced in developing siliques of the lec1-1 mutants, indicating that LEC1 down-regulates FUS3 and ABI3.When LEC1 is overexpressed from an inducible promoter, the expression of numerous genes involved in fatty acid biosynthesis is increased suggesting a role in positive regulation of FA biosynthesis.
OrthologsView orthologs and multiple alignments for LEC1

Proteins

nuclear transcription factor Y subunit B-9
Refseq ID:NP_173616
Protein GI:42562232
UniProt ID:Q9SFD8
mRNA ID:NM_102046
Length:238
RefSeq Status:REVIEWED
MERGAPFSHYQLPKSISELNLDQHSNNPTPMTSSVVVAGAGDKNNGIVVQQQPPCVAREQDQYMPIANVIRIMRKTLPSHAKISDDAKETIQECVSEYIS
FVTGEANERCQREQRKTITAEDILWAMSKLGFDNYVDPLTVFINRYREIETDRGSALRGEPPSLRQTYGGNGIGFHGPSHGLPPPGPYGYGMLDQSMVMG
GGRYYQNGSSGQDESSVGGGSSSSINGMPAFDHYGQYK