LIPID MAPSĀ® Gene/Proteome Database (LMPD)

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LMPD Record

LMP008940

UniProt Annotations

Entry Information
Gene NameG protein alpha q subunit
Protein EntryGNAQ_DROME
UniProt IDP23625
SpeciesDrosophila
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Comment=Additional isoforms seem to exist.; Name=D; Synonyms=F; IsoId=P23625-1; Sequence=Displayed; Name=A; Synonyms=B, C, E, G, H; IsoId=P23625-2; Sequence=VSP_001835, VSP_001836;
FunctionGuanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Could be the transducin analog, an amplifier and one of the transducers of a visual impulse that performs the coupling between opsin and cGMP-phosphodiesterase. Could mediate a subset of olfactory and gustatory responses. {ECO:0000269|PubMed:2125225, ECO:0000269|PubMed:8524786}.
SimilarityBelongs to the G-alpha family. G(q) subfamily. {ECO:0000305}.
Tissue SpecificityIsoform D is expressed only in the retina and ocellus of the adult head. Isoform A is expressed in chemosensory cells of the olfactory and taste structures, including a subset of olfactory and gustatory neurons, and in cells of the central nervous system, including neurons in the lamina ganglionaris. {ECO:0000269|PubMed:2125225, ECO:0000269|PubMed:8524786}.