LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP007469

UniProt Annotations

Entry Information
Gene Namecalmodulin
Protein EntryCALM_YEAST
UniProt IDP06787
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionCalmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. {ECO:0000269|PubMed:10339566}.
InteractionP23287:CNA1; NbExp=3; IntAct=EBI-3976, EBI-12771; Q04439:MYO5; NbExp=7; IntAct=EBI-3976, EBI-11687; P32380:SPC110; NbExp=2; IntAct=EBI-3976, EBI-12369;
MiscellaneousThis protein has three functional calcium-binding sites.
PtmThe N-terminus is blocked.
SimilarityBelongs to the calmodulin family. {ECO:0000305}.
SimilarityContains 4 EF-hand domains. {ECO:0000255|PROSITE- ProRule:PRU00448}.
Subcellular LocationCytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:8247006}.
SubunitComponent of the SPC110 complex containing at least CMD1, SPC29, SPC42 and SCP110. Interacts with SPC110. {ECO:0000269|PubMed:10339566, ECO:0000269|PubMed:8247006}.