LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP007139

UniProt Annotations

Entry Information
Gene NameSla2p
Protein EntrySLA2_YEAST
UniProt IDP33338
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionRequired for cellular morphogenesis and polarization of the cortical cytoskeleton. It might act in concert with proteins such as CDC42 and CDC43 to limit the region of cortical patch formation to the cortex of the bud. Required for the accumulation and/or maintenance of plasma membrane H(+)-ATPase on the cell surface.
InteractionQ12446:LAS17; NbExp=3; IntAct=EBI-17323, EBI-10022;
MiscellaneousPresent with 40600 molecules/cell in log phase SD medium
MiscellaneousPresent with 40600 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Sequence CautionSequence=AAA19161.1; Type=Frameshift; Positions=887, 959; Evidence= ;
Sequence CautionSequence=AAA19161.1; Type=Frameshift; Positions=887, 959; Evidence={ECO:0000305};
SimilarityBelongs to the SLA2 family
SimilarityBelongs to the SLA2 family. {ECO:0000305}.
SimilarityContains 1 ENTH (epsin N-terminal homology) domain
SimilarityContains 1 ENTH (epsin N-terminal homology) domain. {ECO:0000255|PROSITE-ProRule:PRU00243}.
SimilarityContains 1 I/LWEQ domain. {ECO:0000255|PROSITE- ProRule:PRU00292}.
Subcellular LocationCell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00243}. Cytoplasm, cytoskeleton, actin patch. Cytoplasm, cell cortex. Bud tip.
Subcellular LocationCell membrane ; Single-pass membrane protein . Cytoplasm, cytoskeleton, actin patch. Cytoplasm, cell cortex. Bud tip.