LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP007047

UniProt Annotations

Entry Information
Gene NameIvy1p
Protein EntryIVY1_YEAST
UniProt IDQ04934
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionMay be required for vacuolar fusion. Overexpression leads to fragmentation of vacuoles, missorting of the vacuolar enzyme carboxypeptidase Y (CPY) to the exterior of the cell and accumulation of multivesicular bodies inside the cell. {ECO:0000269|PubMed:12553664}.
InteractionSelf; NbExp=2; IntAct=EBI-35255, EBI-35255; P20795:VPS33; NbExp=3; IntAct=EBI-35255, EBI-20395; P32939:YPT7; NbExp=3; IntAct=EBI-35255, EBI-29509;
MiscellaneousPresent with 2840 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Subcellular LocationVacuole membrane {ECO:0000269|PubMed:12553664}; Peripheral membrane protein {ECO:0000269|PubMed:12553664}. Note=Binds to various phospholipids.
SubunitHomomultimer. Interacts with YPT7 and VPS33. {ECO:0000269|PubMed:12553664}.