LIPID MAPSĀ® Gene/Proteome Database (LMPD)

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LMPD Record

LMP007005

UniProt Annotations

Entry Information
Gene NameSfh5p
Protein EntrySFH5_YEAST
UniProt IDP47008
SpeciesYeast (S288c)
Comments
Comment typeDescription
FunctionNon-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. {ECO:0000269|PubMed:10848624, ECO:0000269|PubMed:12869188, ECO:0000269|PubMed:16709158}.
MiscellaneousPresent with 6540 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
SimilarityBelongs to the SFH5 family. {ECO:0000305}.
SimilarityContains 1 CRAL-TRIO domain. {ECO:0000255|PROSITE- ProRule:PRU00056}.
Subcellular LocationCytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.