LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP006687

Gene Information

Entrez Gene ID6653
Gene Namesortilin-related receptor, L(DLR class) A repeats containing
Gene SymbolSORL1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005769 IDA:Alzheimers_University_of_TorontoCearly endosome
GO:0005783 IDA:Alzheimers_University_of_TorontoCendoplasmic reticulum
GO:0005768 IDA:UniProtKBCendosome
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtCextracellular vesicular exosome
GO:0005794 IDA:UniProtKBCGolgi apparatus
GO:0031985 IDA:Alzheimers_University_of_TorontoCGolgi cisterna
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0034362 IEA:UniProtKB-KWClow-density lipoprotein particle
GO:0016020 IDA:UniProtKBCmembrane
GO:0005771 IEA:EnsemblCmultivesicular body
GO:0043025 IEA:EnsemblCneuronal cell body
GO:0005641 IDA:Alzheimers_University_of_TorontoCnuclear envelope lumen
GO:0055037 IMP:Alzheimers_University_of_TorontoCrecycling endosome
GO:0005802 IDA:Alzheimers_University_of_TorontoCtrans-Golgi network
GO:0030306 IPI:Alzheimers_University_of_TorontoFADP-ribosylation factor binding
GO:0001540 IDA:Alzheimers_University_of_TorontoFbeta-amyloid binding
GO:0030169 IPI:BHF-UCLFlow-density lipoprotein particle binding
GO:0004888 TAS:ProtIncFtransmembrane signaling receptor activity
GO:0008219 IEA:UniProtKB-KWPcell death
GO:0016477 IEA:EnsemblPcell migration
GO:0008283 IEA:EnsemblPcell proliferation
GO:0008203 IEA:UniProtKB-KWPcholesterol metabolic process
GO:0006869 IEA:UniProtKB-KWPlipid transport
GO:1902960 IDA:Alzheimers_University_of_TorontoPnegative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902430 IDA:Alzheimers_University_of_TorontoPnegative regulation of beta-amyloid formation
GO:0043407 ISS:Alzheimers_University_of_TorontoPnegative regulation of MAP kinase activity
GO:1902963 IMP:Alzheimers_University_of_TorontoPnegative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902997 ISS:Alzheimers_University_of_TorontoPnegative regulation of neurofibrillary tangle assembly
GO:0050768 ISS:Alzheimers_University_of_TorontoPnegative regulation of neurogenesis
GO:1901215 ISS:Alzheimers_University_of_TorontoPnegative regulation of neuron death
GO:0032091 IDA:Alzheimers_University_of_TorontoPnegative regulation of protein binding
GO:0032460 IMP:Alzheimers_University_of_TorontoPnegative regulation of protein oligomerization
GO:1902948 ISS:Alzheimers_University_of_TorontoPnegative regulation of tau-protein kinase activity
GO:1902771 ISS:Alzheimers_University_of_TorontoPpositive regulation of choline O-acetyltransferase activity
GO:1902955 IMP:Alzheimers_University_of_TorontoPpositive regulation of early endosome to recycling endosome transport
GO:2001137 IMP:Alzheimers_University_of_TorontoPpositive regulation of endocytic recycling
GO:1902953 IMP:Alzheimers_University_of_TorontoPpositive regulation of ER to Golgi vesicle-mediated transport
GO:0045732 IDA:Alzheimers_University_of_TorontoPpositive regulation of protein catabolic process
GO:0070863 IMP:Alzheimers_University_of_TorontoPpositive regulation of protein exit from endoplasmic reticulum
GO:1902966 IMP:Alzheimers_University_of_TorontoPpositive regulation of protein localization to early endosome
GO:0006892 IDA:Alzheimers_University_of_TorontoPpost-Golgi vesicle-mediated transport
GO:0051604 IDA:Alzheimers_University_of_TorontoPprotein maturation
GO:0045053 IDA:Alzheimers_University_of_TorontoPprotein retention in Golgi apparatus
GO:0006605 IMP:UniProtKBPprotein targeting
GO:0000042 IDA:Alzheimers_University_of_TorontoPprotein targeting to Golgi
GO:0006622 IDA:Alzheimers_University_of_TorontoPprotein targeting to lysosome
GO:0006898 TAS:ProtIncPreceptor-mediated endocytosis
GO:0014910 IDA:UniProtKBPregulation of smooth muscle cell migration
GO:0007165 TAS:GOCPsignal transduction