LIPID MAPS® Gene/Proteome Database (LMPD)

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LMPD Record

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LMP000794

UniProt Annotations

Entry Information
Gene Nameglyceronephosphate O-acyltransferase
Protein EntryGNPAT_MOUSE
UniProt IDP98192
SpeciesMouse
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate.
DomainThe HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}.
PathwayMembrane lipid metabolism; glycerophospholipid metabolism.
SimilarityBelongs to the GPAT/DAPAT family. {ECO:0000305}.
Subcellular LocationPeroxisome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}. Note=Exclusively localized to the lumenal side of the peroxisomal membrane. {ECO:0000250}.
SubunitMay be part of a heterotrimeric complex composed of DAP- AT, ADAP-S and a modified form of DAP-AT.
Tissue SpecificityHighly expressed in liver and testis. Lower levels in heart, brain, lung and kidney. Detected in spleen.