LMPD Database

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LMP013615

UniProt Annotations

Entry Information
Gene NameABO-family member 5
Protein EntryGTA1L_RAT
UniProt IDG3V9Q9
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityUDP-alpha-D-galactose + beta-D-galactosyl- (1->4)-beta-N-acetyl-D-glucosaminyl-R = UDP + alpha-D-galactosyl- (1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R.
CofactorName=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence= ;
DomainThe conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphate group of UDP and may also have a role in catalysis (By similarity)
FunctionSynthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid
MiscellaneousThis gene is not expressed in humans.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 6 family
Subcellular LocationGolgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein . Note=Membrane-bound form in trans cisternae of Golgi