LMPD Database

LMP013614

UniProt Annotations

Entry Information
Gene Namephosphatidic acid phosphatase type 2 domain containing 2
Protein EntryPPAC2_RAT
UniProt IDQ66H88
SpeciesRat
Comments
Comment typeDescription
FunctionPhosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid (By similarity)
SimilarityBelongs to the PA-phosphatase related phosphoesterase family
Subcellular LocationMembrane ; Multi-pass membrane protein .