LMPD Database

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LMP013575

UniProt Annotations

Entry Information
Gene NameELOVL fatty acid elongase 2
Protein EntryELOV2_RAT
UniProt IDD4A612
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityA very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2)
DomainThe di-lysine motif may confer endoplasmic reticulum localization
FunctionCondensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (n-6 and n-3 C18-, C20- and C22-PUFA)
PathwayLipid metabolism; polyunsaturated fatty acid biosynthesis
SimilarityBelongs to the ELO family
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein .