LMPD Database

LMP013077

Gene Information

Entrez Gene ID	291567
Gene Name	peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Gene Symbol	Ppargc1b
Species	Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0016592	IEA:Ensembl	C	mediator complex
GO:0005739	IEA:Ensembl	C	mitochondrion
GO:0005634	ISS:UniProtKB	C	nucleus
GO:0050682	ISS:UniProtKB	F	AF-2 domain binding
GO:0030374	ISS:UniProtKB	F	ligand-dependent nuclear receptor transcription coactivator activity
GO:0000166	IEA:InterPro	F	nucleotide binding
GO:0030546	IEA:Ensembl	F	receptor activator activity
GO:0003723	IEA:UniProtKB-KW	F	RNA binding
GO:0001104	IEA:Ensembl	F	RNA polymerase II transcription cofactor activity
GO:0007015	IEA:Ensembl	P	actin filament organization
GO:0060346	IEA:Ensembl	P	bone trabecula formation
GO:0034614	IEA:Ensembl	P	cellular response to reactive oxygen species
GO:0030520	ISS:UniProtKB	P	intracellular estrogen receptor signaling pathway
GO:0045892	IEA:Ensembl	P	negative regulation of transcription, DNA-templated
GO:0001503	IEA:Ensembl	P	ossification
GO:0010694	IEA:Ensembl	P	positive regulation of alkaline phosphatase activity
GO:0045780	IEA:Ensembl	P	positive regulation of bone resorption
GO:0045672	IEA:Ensembl	P	positive regulation of osteoclast differentiation
GO:0042327	IEA:Ensembl	P	positive regulation of phosphorylation
GO:0045944	ISS:UniProtKB	P	positive regulation of transcription from RNA polymerase II promoter
GO:0006355	ISS:UniProtKB	P	regulation of transcription, DNA-templated
GO:0051591	IEP:RGD	P	response to cAMP
GO:0051384	IEP:RGD	P	response to glucocorticoid
GO:0006390	IEA:Ensembl	P	transcription from mitochondrial promoter

REACTOME Pathway Links

REACTOME Pathway ID	Description
5953288	Fatty acid, triacylglycerol, and ketone body metabolism
5953250	Metabolism
5953289	Metabolism of lipids and lipoproteins
5953600	Mitochondrial biogenesis
5953601	Organelle biogenesis and maintenance
5954333	PPARA activates gene expression
5954222	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
5953599	Transcriptional activation of mitochondrial biogenesis