LMPD Database

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LMP013022

UniProt Annotations

Entry Information
Gene Namephosphatidylinositol glycan anchor biosynthesis, class X
Protein EntryPIGX_RAT
UniProt IDQ60GF7
SpeciesRat
Comments
Comment typeDescription
CautionPubMed:15635094 reported that the initiator methionine is coded by an unusual start codon, CTG
FunctionEssential component of glycosylphosphatidylinositol- mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM
PathwayGlycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
PtmN-glycosylated
Sequence CautionSequence=BAD61008.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical CTG leucine codon.; Evidence= ;
SimilarityBelongs to the PIGX family
Subcellular LocationEndoplasmic reticulum membrane ; Single-pass type I membrane protein .
SubunitInteracts with PIGM.