LMPD Database

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LMP012994

UniProt Annotations

Entry Information
Gene Namesterol O-acyltransferase 2
Protein EntrySOAT2_RAT
UniProt IDQ7TQM4
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + cholesterol = CoA + cholesterol ester.
FunctionPlays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa (By similarity)
SimilarityBelongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily
Subcellular LocationEndoplasmic reticulum membrane; Multi-pass membrane protein.
SubunitMay form homo- or heterodimers