LMPD Database

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LMP012972

UniProt Annotations

Entry Information
Gene Namepatatin-like phospholipase domain containing 7
Protein EntryPLPL7_RAT
UniProt IDQ5BK26
SpeciesRat
Comments
Comment typeDescription
CautionIt is uncertain whether Met-1 or Met-27 is the initiator
FunctionSerine hydrolase, whose specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy
Sequence CautionSequence=AAH91230.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the NTE family
SimilarityContains 1 patatin domain
SimilarityContains 3 cyclic nucleotide-binding domains
Subcellular LocationMembrane ; Single-pass membrane protein {ECO:0000305}. Nucleus membrane ; Single-pass membrane protein . Mitochondrion membrane {ECO:0000305}; Single-pass membrane protein . Lysosome membrane ; Single-pass membrane protein {ECO:0000305}. Microsome membrane ; Single-pass membrane protein . Note=Found in the nuclear, mitochondrial, lysosomal, and microsomal fractions
Tissue SpecificityExpressed in the brain, liver, kidney, lung and testis