LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP012900

UniProt Annotations

Entry Information
Gene Name2,4-dienoyl CoA reductase 1, mitochondrial
Protein EntryDECR_RAT
UniProt IDQ64591
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityTrans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH.
FunctionAuxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA.
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily
Subcellular LocationMitochondrion.
SubunitHomotetramer