LMPD Database

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LMP012888

UniProt Annotations

Entry Information
Gene Namelysophosphatidic acid receptor 1
Protein EntryLPAR1_RAT
UniProt IDP61794
SpeciesRat
Comments
Comment typeDescription
FunctionReceptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation (By similarity)
SimilarityBelongs to the G-protein coupled receptor 1 family
Subcellular LocationCell surface . Cell membrane; Multi-pass membrane protein. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co- localizes with RALA in the endocytic vesicles
SubunitInteracts with RALA and ADRBK1