LMPD Database

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LMP012790

UniProt Annotations

Entry Information
Gene NameUDP-glucose ceramide glucosyltransferase
Protein EntryCEGT_RAT
UniProt IDQ9R0E0
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityUDP-glucose + N-acylsphingosine = UDP + D- glucosyl-N-acylsphingosine
FunctionCatalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. Able to use UDP-galactose to synthesize galactosylceramide with 10% of efficiency with which it utilizes UDP-glucose. May also serve as a "flippase"
PathwayLipid metabolism; sphingolipid metabolism.
SimilarityBelongs to the glycosyltransferase 2 family
Subcellular LocationGolgi apparatus membrane ; Multi-pass membrane protein .