LMPD Database

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LMP012776

Record overview

LMPD IDLMP012776
Gene ID81924
SpeciesMacaca mulata (Rhesus monkey)
Gene Namecytochrome P450, family 8, subfamily b, polypeptide 1
Gene SymbolCyp8b1
Alternate names7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; cytochrome P450 8b1 sterol 12 alpha-hydrolase; cytochrome P450, 8b1, sterol 12 alpha-hydrolase;
Chromosome8
Map Location8q32
Summarymember of the cytochrome P450 enzyme superfamily; endoplasmic reticulum membrane protein; plays a role in sterol metabolism; human homolog is unique among cytochrome P450 genes in that it is intronless [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Cyp8b1

Proteins

7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase precursor
Refseq ID:NP_112520
Protein GI:13676851
UniProt ID:Q9WVT5
mRNA ID:NM_031241
Length:499
RefSeq Status:
MLWGSVLGALLMAVGCLCLSLLPRHRRPWEPPLDKGFVPWLGHTMAFRKNMFEFLKGMRAKHGDVFTLQLGGQYFTFVMDPLSFGPIIKSTQKVLDFVTY
ARELVFKVFGYQSMDEDHQMLHVASTKHLMGQGLEDLNRAMLDSLSLVMLGPKGRSLGARSWCEDGLFHFCYSILFKAGFLSLFGCTKDKEQDLDEADEL
FRKFRRFDLLFPRFVYSLLGPLEWVEVSQLQRLFHQRLSVEQNLEKDGISNWLGFMLRFLRERGMASSMQDKFNFMMLWASQGNTGPTCFWALLFLLKHQ
DAMKAVREEATRVLGEARLEAETSFAFTLSALKCTPVLDSVMEETLRLCATPTLLGVVQEDYVLKMASGQEYQIRRGDKVALFPYLSVHMDPDIHPEPTT
FKYNRFLNPDGTRKVDFYKSGKKIHHYNMPWGSGVSICPGRFFAPSEMKTFVLLMVMYFDFELVDPDMPVPPIDPRRWGFGTSQPSHEVRFRYRLKPMQ
 

sig_peptide: 1..18
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1837
peptide sequence: 
MLWGSVLGALLMAVGCLC