LMPD Database

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LMP012775

UniProt Annotations

Entry Information
Gene Namefucosyltransferase 1
Protein EntryFUT1_RAT
UniProt IDQ10980
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityGDP-beta-L-fucose + beta-D-galactosyl-(1->3)- N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta- D-glucosyl-(1<->1)-ceramide = GDP + alpha-L-fucosyl-(1->2)-beta-D- galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D- galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.
MiscellaneousThere are two genes (Fut1 and Fut2) which encode galactoside 2-L-fucosyltransferase. They are expressed in a tissue-specific manner with expression restricted to cells of mesodermal or endodermal origin respectively.
PathwayProtein modification; protein glycosylation.
SimilarityBelongs to the glycosyltransferase 11 family
Subcellular LocationGolgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein . Note=Membrane-bound form in trans cisternae of Golgi