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LMP012696

Record overview

LMPD IDLMP012696
Gene ID64317
SpeciesMacaca mulata (Rhesus monkey)
Gene Nameglutathione peroxidase 3
Gene SymbolGpx3
SynonymsGpxp; GPx-3; GPx-P; GSHPx-3; GSHPx-P;
Alternate namesglutathione peroxidase 3; plasma glutathione peroxidase;
Chromosome10
Map Location10q22
EC Number1.11.1.9
SummaryThis gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. The active site of this enzyme contains a selenocysteine residue, which is encoded by UGA that normally signals translation termination. This gene is highly expressed in the kidney where it may play a role in protecting the kidney from oxidative damage. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for Gpx3

Proteins

glutathione peroxidase 3 precursor
Refseq ID:NP_071970
Protein GI:41053837
UniProt ID:P23764
mRNA ID:NM_022525
Length:226
RefSeq Status:
MARILRASCLLSLLLAGFVPPGRGQEKSKTDCHGGMSGTIYEYGALTIDGEEYIPFKQYAGKYILFVNVASYUGLTDQYLELNALQEELGPFGLVILGFP
CNQFGKQEPGENSEILPSLKYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTAELLGSPGRLFWEPMKIHDIRWNFEKFLVGPDGIPIMRWYH
RTTVSNVKMDILSYMRRQAALGARGK
 

sig_peptide: 1..24
inference: non-experimental evidence, no additional details recorded
note: Potential; propagated from UniProtKB/Swiss-Prot (P23764.2)
calculated_mol_wt: 2512
peptide sequence: 
MARILRASCLLSLLLAGFVPPGRG

sig_peptide: 1..19
calculated_mol_wt: 2048
peptide sequence: 
MARILRASCLLSLLLAGFV

mat_peptide: 20..226
product: glutathione peroxidase 3
calculated_mol_wt: 23395
peptide sequence: 
PPGRGQEKSKTDCHGGMSGTIYEYGALTIDGEEYIPFKQYAGKYILFVNVASYUGLTDQYLELNALQEELGPFGLVILGFPCNQFGKQEPGENSEILPSL
KYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTAELLGSPGRLFWEPMKIHDIRWNFEKFLVGPDGIPIMRWYHRTTVSNVKMDILSYMRRQA
ALGARGK

mat_peptide: 25..226
product: Glutathione peroxidase 3
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P23764.2)
calculated_mol_wt: 22930
peptide sequence: 
QEKSKTDCHGGMSGTIYEYGALTIDGEEYIPFKQYAGKYILFVNVASYUGLTDQYLELNALQEELGPFGLVILGFPCNQFGKQEPGENSEILPSLKYVRP
GGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTAELLGSPGRLFWEPMKIHDIRWNFEKFLVGPDGIPIMRWYHRTTVSNVKMDILSYMRRQAALGAR
GK