LMPD Database

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LMP012608

UniProt Annotations

Entry Information
Gene Namelipocalin 5
Protein EntryLCN5_RAT
UniProt IDP06911
SpeciesRat
Comments
Comment typeDescription
FunctionAssociates with spermatozoa in the epididymal fluid but does not bind tightly to them. Binds both all-trans and 9-cis retinoic acid. May act as a retinoid carrier protein which is required for epididymal function and/or sperm maturation.
PtmThe N-terminus of form C is probably blocked.
PtmThere are two similar, immunologically cross-reacting forms of this protein, designated B and C, which probably result from different processing of the amino end.
SimilarityBelongs to the calycin superfamily. Lipocalin family
Subcellular LocationSecreted. Note=Synthesized in the proximal part of the epididymis and secreted into the epididymal fluid.
Tissue SpecificitySynthesized exclusively in the proximal part (caput epididymidis) of the epididymis. It makes up a substantial part of the total protein in the epididymal luminal fluid and binds to the sperm membrane.