LMPD Database

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LMP012590

UniProt Annotations

Entry Information
Gene Namesphingosine-1-phosphate receptor 2
Protein EntryS1PR2_RAT
UniProt IDP47752
SpeciesRat
Comments
Comment typeDescription
FunctionReceptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.
SimilarityBelongs to the G-protein coupled receptor 1 family
Subcellular LocationCell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in all developing tissues with highest levels detected in primitive, transformed cells. Relative abundance: lung > kidney = skin = gut > spleen > brain > liver.