LMPD Database

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LMP012551

Record overview

LMPD IDLMP012551
Gene ID25706
SpeciesMacaca mulata (Rhesus monkey)
Gene Namecholecystokinin B receptor
Gene SymbolCckbr
SynonymsCck2r; Cholrec;
Alternate namesgastrin/cholecystokinin type B receptor; CCK-BR; CCK2-R; CCK2 receptor; CCK-B receptor; CCK(B) receptor; cholecystokinin-2 receptor;
Chromosome1
Map Location1q33
SummaryCholecystokinin was one of the first gastrointestinal peptides discovered in the mammalian brain. Cholecystokinin receptors are members of the G protein-coupled receptor superfamily, stimulating phosphatidylinositol turnover and intracellular calcium mobilization. This gene encodes a cholecystokinin receptor of the B subtype. These receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for Cckbr

Proteins

gastrin/cholecystokinin type B receptor
Refseq ID:NP_037297
Protein GI:6978617
UniProt ID:P30553
mRNA ID:NM_013165
Length:452
RefSeq Status:
MELLKLNRSVQGPGPGSGSSLCRPGVSLLNSSSAGNLSCDPPRIRGTGTRELEMAIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSD
LLLAVACMPFTLLPNLMGTFIFGTVICKAISYLMGVSVSVSTLNLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTMVQPVGP
RVLQCMHRWPSARVQQTWSVLLLLLLFFIPGVVIAVAYGLISRELYLGLHFDGENDSETQSRARNQGGLPGGAAPGPVHQNGGCRPVTSVAGEDSDGCCV
QLPRSRLEMTTLTTPTPGPVPGPRPNQAKLLAKKRVVRMLLVIVLLFFLCWLPVYSVNTWRAFDGPGAQRALSGAPISFIHLLSYVSACVNPLVYCFMHR
RFRQACLDTCARCCPRPPRARPQPLPDEDPPTPSIASLSRLSYTTISTLGPG