LMPD Database

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LMP012525

UniProt Annotations

Entry Information
Gene Namesolute carrier family 18 (vesicular monoamine transporter), member 2
Protein EntryVMAT2_RAT
UniProt IDQ01827
SpeciesRat
Comments
Comment typeDescription
FunctionInvolved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.
SimilarityBelongs to the major facilitator superfamily. Vesicular transporter family
Subcellular LocationCytoplasmic vesicle membrane; Multi-pass membrane protein.
SubunitInteracts with SLC6A3
Tissue SpecificityBrainstem and stomach.