GO ID | Source | Type | Description |
GO:0045179 |
IEA:Ensembl | C | apical cortex |
GO:0016324 |
IEA:Ensembl | C | apical plasma membrane |
GO:0043203 |
IEA:Ensembl | C | axon hillock |
GO:0005911 |
ISS:UniProtKB | C | cell-cell junction |
GO:0031252 |
IDA:RGD | C | cell leading edge |
GO:0005737 |
IDA:RGD | C | cytoplasm |
GO:0005829 |
IDA:RGD | C | cytosol |
GO:0005768 |
IEA:UniProtKB-KW | C | endosome |
GO:0070062 |
IEA:Ensembl | C | extracellular vesicular exosome |
GO:0043231 |
IDA:RGD | C | intracellular membrane-bounded organelle |
GO:0045121 |
IDA:RGD | C | membrane raft |
GO:0005815 |
IEA:Ensembl | C | microtubule organizing center |
GO:0035748 |
IEA:Ensembl | C | myelin sheath abaxonal region |
GO:0005635 |
IEA:Ensembl | C | nuclear envelope |
GO:0016363 |
IEA:Ensembl | C | nuclear matrix |
GO:0048471 |
IDA:RGD | C | perinuclear region of cytoplasm |
GO:0005886 |
IDA:UniProtKB | C | plasma membrane |
GO:0043234 |
IDA:RGD | C | protein complex |
GO:0005923 |
IEA:Ensembl | C | tight junction |
GO:0071889 |
IPI:RGD | F | 14-3-3 protein binding |
GO:0005524 |
IDA:RGD | F | ATP binding |
GO:0043274 |
IPI:RGD | F | phospholipase binding |
GO:0015459 |
IMP:RGD | F | potassium channel regulator activity |
GO:0019904 |
IPI:RGD | F | protein domain specific binding |
GO:0004672 |
TAS:RGD | F | protein kinase activity |
GO:0019901 |
IPI:RGD | F | protein kinase binding |
GO:0004697 |
IDA:RGD | F | protein kinase C activity |
GO:0004674 |
IDA:RGD | F | protein serine/threonine kinase activity |
GO:0008270 |
IEA:InterPro | F | zinc ion binding |
GO:0031532 |
IMP:RGD | P | actin cytoskeleton reorganization |
GO:0031584 |
IMP:RGD | P | activation of phospholipase D activity |
GO:0032148 |
IMP:RGD | P | activation of protein kinase B activity |
GO:0016477 |
IMP:RGD | P | cell migration |
GO:0007166 |
IMP:RGD | P | cell surface receptor signaling pathway |
GO:0034613 |
IMP:RGD | P | cellular protein localization |
GO:0032869 |
IMP:RGD | P | cellular response to insulin stimulus |
GO:0030010 |
IMP:UniProtKB | P | establishment of cell polarity |
GO:0006954 |
IEA:UniProtKB-KW | P | inflammatory response |
GO:0008286 |
IMP:RGD | P | insulin receptor signaling pathway |
GO:0035556 |
IDA:RGD | P | intracellular signal transduction |
GO:0007616 |
IMP:RGD | P | long-term memory |
GO:0060291 |
IMP:UniProtKB | P | long-term synaptic potentiation |
GO:0051899 |
IMP:RGD | P | membrane depolarization |
GO:0060081 |
IMP:RGD | P | membrane hyperpolarization |
GO:0000226 |
IEA:Ensembl | P | microtubule cytoskeleton organization |
GO:0043066 |
IDA:RGD | P | negative regulation of apoptotic process |
GO:0051346 |
IDA:RGD | P | negative regulation of hydrolase activity |
GO:0046627 |
IEA:Ensembl | P | negative regulation of insulin receptor signaling pathway |
GO:0050732 |
IEA:Ensembl | P | negative regulation of peptidyl-tyrosine phosphorylation |
GO:0031333 |
IEA:Ensembl | P | negative regulation of protein complex assembly |
GO:1990138 |
IEA:Ensembl | P | neuron projection extension |
GO:0018105 |
IDA:RGD | P | peptidyl-serine phosphorylation |
GO:0001954 |
IMP:RGD | P | positive regulation of cell-matrix adhesion |
GO:0008284 |
IMP:RGD | P | positive regulation of cell proliferation |
GO:0070374 |
IMP:UniProtKB | P | positive regulation of ERK1 and ERK2 cascade |
GO:2000463 |
IDA:UniProtKB | P | positive regulation of excitatory postsynaptic membrane potential |
GO:0046326 |
IMP:RGD | P | positive regulation of glucose import |
GO:0046628 |
IMP:UniProtKB | P | positive regulation of insulin receptor signaling pathway |
GO:2001181 |
ISS:UniProtKB | P | positive regulation of interleukin-10 secretion |
GO:2000667 |
ISS:UniProtKB | P | positive regulation of interleukin-13 secretion |
GO:0032753 |
ISS:UniProtKB | P | positive regulation of interleukin-4 production |
GO:2000664 |
ISS:UniProtKB | P | positive regulation of interleukin-5 secretion |
GO:0051092 |
IMP:UniProtKB | P | positive regulation of NF-kappaB transcription factor activity |
GO:0051222 |
IMP:RGD | P | positive regulation of protein transport |
GO:0050806 |
IMP:RGD | P | positive regulation of synaptic transmission |
GO:2000553 |
ISS:UniProtKB | P | positive regulation of T-helper 2 cell cytokine production |
GO:0045630 |
ISS:UniProtKB | P | positive regulation of T-helper 2 cell differentiation |
GO:0051291 |
IPI:RGD | P | protein heterooligomerization |
GO:0070528 |
IMP:RGD | P | protein kinase C signaling |
GO:0072659 |
IEA:Ensembl | P | protein localization to plasma membrane |
GO:0006468 |
IDA:RGD | P | protein phosphorylation |
GO:0007165 |
IDA:RGD | P | signal transduction |
GO:0047496 |
IMP:RGD | P | vesicle transport along microtubule |
REACTOME Pathway ID | Description |
---|
5953253 | Disease |
5953651 | GPVI-mediated activation cascade |
5953645 | Hemostasis |
5953818 | Loss of Function of SMAD2/3 in Cancer |
5953821 | Loss of Function of SMAD4 in Cancer |
5953827 | Loss of Function of TGFBR1 in Cancer |
5953824 | Loss of Function of TGFBR2 in Cancer |
5953644 | Platelet activation, signaling and aggregation |
5953816 | Signaling by TGF-beta Receptor Complex |
5953819 | Signaling by TGF-beta Receptor Complex in Cancer |
5953420 | Signaling by VEGF |
5953381 | Signal Transduction |
5953822 | SMAD2/3 MH2 Domain Mutants in Cancer |
5953817 | SMAD2/3 Phosphorylation Motif Mutants in Cancer |
5953820 | SMAD4 MH2 Domain Mutants in Cancer |
5954545 | TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
5953826 | TGFBR1 KD Mutants in Cancer |
5953828 | TGFBR1 LBD Mutants in Cancer |
5953825 | TGFBR2 Kinase Domain Mutants in Cancer |
5953823 | TGFBR2 MSI Frameshift Mutants in Cancer |
5953419 | VEGFA-VEGFR2 Pathway |
5953418 | VEGFR2 mediated cell proliferation |