LMPD Database

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LMP012505

UniProt Annotations

Entry Information
Gene Nameapolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Protein EntryABEC1_RAT
UniProt IDP38483
SpeciesRat
Comments
Comment typeDescription
CofactorName=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence= ;
FunctionCatalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
SimilarityBelongs to the cytidine and deoxycytidylate deaminase family
Subcellular LocationCytoplasm .
SubunitHomodimer. Part of the apolipoprotein B mRNA editing complex with A1CF. Interacts with SYNCRIP. Interacts with HNRPAB (By similarity)
Tissue SpecificityExpressed in the liver as well as small intestine.