LMPD Database

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LMP012468

UniProt Annotations

Entry Information
Gene Namecytochrome P450, family 2, subfamily e, polypeptide 1
Protein EntryCP2E1_RAT
UniProt IDP05182
SpeciesRat
Comments
Comment typeDescription
Catalytic Activity4-nitrophenol + NADPH + O(2) = 4-nitrocatechol + NADP(+) + H(2)O.
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Evidence= ;
FunctionMetabolizes several precarcinogens, drugs, and solvents to reactive metabolites
InductionBy ethanol.
SimilarityBelongs to the cytochrome P450 family
Subcellular LocationEndoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.