LMPD Database

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LMP012412

Record overview

LMPD IDLMP012412
Gene ID24530
SpeciesMacaca mulata (Rhesus monkey)
Gene Namelecithin cholesterol acyltransferase
Gene SymbolLcat
Alternate namesphosphatidylcholine-sterol acyltransferase; Lecithin-cholesterol acyltransferase; phospholipid-cholesterol acyltransferase;
Chromosome19
Map Location19q12
EC Number2.3.1.43
Summaryenzyme involved in the metabolism of plasma lipoproteins [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Lcat

Proteins

phosphatidylcholine-sterol acyltransferase precursor
Refseq ID:NP_058720
Protein GI:158262015
UniProt ID:O35849
mRNA ID:NM_017024
Length:440
RefSeq Status:
MGLPGSPWQWVLLLLGLLLPPATSFWLLNVLFPPHTTPKAELSNHTRPVILVPGCMGNRLEAKLDKPNVVNWLCYRKTEDFFTIWLDFNMFLPLGVDCWI
DNTRVVYNRSSGHMSNAPGVQIRVPGFGKTYSVEYLDDNKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLAPRQQDEYYQKLAGLVEEMYAAYGKPVF
LIGHSLGCLHVLHFLLRQPQSWKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPIMSNIKLREEQRITTTSPWMFPAHHVWPEDHVFISTPNFNYTGQ
DFERFFADLHFEEGWHMFLQSRDLLAGLPAPGVEVYCLYGVGMPTAHTYIYDHNFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQAVHLLPMNGTD
HLNMVFSNKTLEHINAILLGAYRHGTPKSPTASLGPPTKE
 

sig_peptide: 1..24
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2560
peptide sequence: 
MGLPGSPWQWVLLLLGLLLPPATS

mat_peptide: 25..440
product: Phosphatidylcholine-sterol acyltransferase
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P18424.1)
calculated_mol_wt: 47340
peptide sequence: 
FWLLNVLFPPHTTPKAELSNHTRPVILVPGCMGNRLEAKLDKPNVVNWLCYRKTEDFFTIWLDFNMFLPLGVDCWIDNTRVVYNRSSGHMSNAPGVQIRV
PGFGKTYSVEYLDDNKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLAPRQQDEYYQKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLHFLLRQPQSWKD
HFIDGFISLGAPWGGSIKPMRILASGDNQGIPIMSNIKLREEQRITTTSPWMFPAHHVWPEDHVFISTPNFNYTGQDFERFFADLHFEEGWHMFLQSRDL
LAGLPAPGVEVYCLYGVGMPTAHTYIYDHNFPYKDPVAALYEDGDDTVATRSTELCGQWQGRQSQAVHLLPMNGTDHLNMVFSNKTLEHINAILLGAYRH
GTPKSPTASLGPPTKE